Bioactivity of Endophytic Fungi Isolated from Branch of Jambu Mawar (Syzygium jambos (L.) Alston)

Endophytic fungi isolated from medicinal plants have high diversity and the secondary metabolites produced biological activity. been subject of many studies on their activity, one which is jambu mawar (Syzygium jambos (L.) Alston). S. has long used as a traditional medicine to treat infections caused by pathogenic bacteria in parts world, including South Sumatra. This study purposed explore endophytic branches jambos, antibacterial activity extracts, determination structure compounds, active compounds selected fungi. Observations morphological characteristics were macroscopically microscopically. The fungal extracts then tested for antimicrobial against test Staphylococcus aureus, Bacillus subtilis, Salmonella typhi, Escherichia coli using Kirby-Bauer paper disk diffusion method. Isolation pure gravity chromatography column, compound determined based 1H-NMR, 13C-NMR, HMQC, HMBC spectroscopy. Four fungi, code SJC1–4, branch jambos. results macroscopic microscopic characterization showed three genera Botryosphaeria, Trichothecium, Aspergillus. isolate SJC1 exhibited strong Gram-positive moderate Gram-negative bacteria, while SJC2–4 four bacteria. Molecular identification revealed that it was Botryosphaeria mamane. SJC1’s yielded 1, identified 5-acetyl-6-hydroxy-3-methyl-2H-pyran-2-one. thought properties.